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You’re not alone in worrying about this. The person writing the post is three weeks into the lowest starting dose of Wegovy (0.25 mg) and says they’re getting progressively more nauseous and full, to the point where they can barely eat 1,000 calories a day. They’re also worried because the scale hasn’t moved and they’re anxious about moving up to the next dose. They’re asking whether to call their doctor or just “push through.” Wegovy is a brand name for semaglutide, a medication that mimics a natural gut hormone involved in appetite and digestion. In plain terms, it tricks parts of your body and brain into feeling less hungry and slowing how fast your stomach empties. Doctors use it for chronic weight management and it’s given as a once-weekly injection. People often start at a low dose for a few weeks so their bodies can adjust before the dose is increased. What this post describes fits known effects of semaglutide: nausea, early fullness, and reduced appetite are common, especially when you first start or when the dose is raised. Clinical trials and prescribing information report these side effects in many people; for most they lessen over time. The details matter here: the report is a single person’s experience, not a controlled study. We don’t know their medical history, other medications, or how well they’re staying hydrated and nourished. The fact they’re already eating much less but haven’t seen weight change yet isn’t unusual early on — weight can lag, and fluid shifts or timing of measurements matter. Why this matters to you or others: severe nausea and being unable to meet basic calorie or fluid needs can be dangerous. If someone is eating under 1,000 calories and feeling sick frequently, they can become weak, dehydrated, lightheaded, or develop nutrient deficits. It also affects quality of life: if the medication makes daily functioning hard, that changes the risk–benefit balance. People who are concerned before a dose increase should consider contacting their prescriber for advice rather than automatically continuing upward. Important caveats and safety notes: semaglutide can cause persistent nausea, vomiting, or constipation. It can also sometimes lead to low blood sugar if combined with certain diabetes drugs. People with a history of pancreatitis, certain thyroid cancers, or severe gastrointestinal disease need careful evaluation. Because this is one person’s report, it can’t predict what everyone will experience. Practical steps: reach out to the clinician who prescribed Wegovy. They may recommend staying at the current dose longer, managing symptoms with diet changes (smaller, blander meals, more fluids), or prescribing anti-nausea remedies. If you’re faint, unable to keep fluids down, or losing weight too quickly, seek medical attention promptly. Bottom line: the symptoms described are a known effect of starting Wegovy, but because they’re interfering with eating and wellbeing, it’s wise to contact the prescribing doctor before increasing the dose.
Source: r/Semaglutide