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Someone started a prescription GLP-1 drug (the class that includes medicines like Ozempic and Wegovy) and after two weeks on the lowest dose they say their appetite is almost gone most days. They were already eating less for weight loss through Weight Watchers and now combine that with the drug. Because their hunger is so suppressed they’re not reaching the calorie target they expected for a safe 1–2 pound weight loss; instead of about 2,500 calories they’re only eating around 1,700 or less per day. GLP‑1 drugs are man-made versions of a natural hormone your gut makes after you eat. That hormone helps slow how fast your stomach empties and sends signals to the brain that reduce hunger. So when people take these medicines they often feel less hungry, feel full sooner, and sometimes eat a lot less without trying. They’re prescribed for diabetes and for helping with weight loss when used under a doctor’s care. What this post actually shows is a real-world, early experience — not a formal study. It’s a single person’s report after about two weeks on a low dose. That’s enough time to notice appetite changes, but it doesn’t tell us long-term effects or how typical this is. The size of the change they report is big: dropping from a planned 2,500 calories to about 1,700 daily is a substantial shortfall. Clinically, that level of reduced intake can lead to faster weight loss than intended and could create energy or nutrient gaps if it continues. Why this matters: people using GLP‑1s should expect appetite suppression, and that can be a good thing if your goal is weight loss. But it can also lead to eating less than your body needs, especially if you were already on a reduced-calorie plan. If you’re exercising, have a job that requires energy, are trying to maintain muscle, or have medical issues, too-low calorie intake can cause fatigue, dizziness, slowed metabolism, or muscle loss. So anyone starting these drugs needs to watch not just the scale but how they feel, and talk with their prescribing clinician about adjusting targets or the dose. Caveats and risks: this is anecdotal, not a clinical trial, so it’s just one person’s experience. GLP‑1 drugs can cause side effects like nausea, constipation, or stomach discomfort. They can also make people under-eat without noticing, which raises risks for nutrient deficiencies or inappropriate rapid weight loss. These drugs are prescription-only; don’t self-medicate. If you or someone else is struggling to meet calorie needs, feeling weak or faint, or losing weight too fast, contact your doctor. They may recommend dose changes, nutritional guidance, or monitoring. Bottom line: GLP‑1 medications can dramatically blunt appetite — useful for weight loss, but they can also make it hard to eat enough; check in with your clinician if intake or symptoms become concerning.
Source: r/Semaglutide