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Someone on a public forum shared that they’ve lost a lot of weight over the last year and that tirzepatide helped them get most of the way there. They started around 348 pounds and are now about 235 pounds. Lately their weight loss has slowed: what used to be 8–10 pounds a month is down to roughly 4–8 pounds every two months. They’re also noticing more hunger while taking a 10 mg dose, and they’re worried about what happens next. Tirzepatide is a prescription medication that’s been used to treat type 2 diabetes and, more recently, for weight loss. In plain terms, it’s a lab-made drug that acts like two natural hormones from the gut that help control blood sugar and appetite. Those hormones talk to your brain to make you feel less hungry and to slow the emptying of your stomach. People often hear it compared to Ozempic or Wegovy, which are drugs that mimic a single gut hormone; tirzepatide combines effects on two pathways, which can produce stronger appetite-suppressing and blood-sugar effects. The person’s report is a single real-world experience, not a clinical trial. Clinical studies of tirzepatide have shown large average weight losses for many people, but how much someone loses and how fast it happens can vary. It’s common for weight loss to be faster at first and then slow down; your body adapts. In this case the initial loss was dramatic and then tapered, which fits a pattern seen in research and other users. The user also says hunger has increased on a 10 mg dose, which could mean the drug’s appetite effects are wearing off a bit for them or that their body is pushing back as weight comes down. Why this matters: for someone trying to lose a lot of weight, tirzepatide can be a powerful tool that makes significant loss possible where diet and exercise alone didn’t work. Slowing weight loss doesn’t mean failure — it may simply be the new normal as you approach a lower weight. People worried about plateaus or returning hunger should know these are common. This matters most for people considering or already on the drug, and for clinicians helping patients set realistic expectations and adjust plans over time. Important caveats: this is one person’s report, not a guideline. Tirzepatide is a prescription medication with possible side effects like nausea, diarrhea, and other digestive issues; it can affect blood sugar and needs medical supervision, especially if you have other health conditions. Long-term effects beyond current study periods are still being studied. Dosing changes or stopping the drug can cause weight regain for some people, and not everyone responds the same way. If hunger increases or progress stalls, the safe step is to talk with a prescribing clinician about dose adjustments, behavioral supports, or complementary strategies rather than making changes alone. Bottom line: tirzepatide can lead to big weight loss for some people, but slowing and returning hunger are common as you get lighter, and any changes should be managed with medical guidance.
Source: r/Mounjaro