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Someone asked whether they can mix two peptides—GHK and AHK—into over‑the‑counter products from The Ordinary to use them on skin and hair, and how much to add. They’re new to peptides and want to know if this do‑it‑yourself approach is acceptable and safe. GHK and AHK are short chains of amino acids (peptides). GHK‑Cu is a peptide linked to copper that’s marketed for skin benefits like improving appearance and wound healing in some lab studies. AHK is a related peptide sequence sometimes mentioned for hair because it may affect hair follicles in lab experiments. These are not miracle drugs; they are small, biologically active fragments that researchers study because they can signal cells to do particular things. The real evidence is limited. Most studies on GHK and AHK are in test tubes or animals, or small, low‑quality human trials. That means we have hints that they might help collagen production, reduce inflammation, or influence hair growth, but the results are neither strong nor consistent across large, well‑controlled human studies. The snippet you shared is just a question from a consumer; it doesn’t provide clinical data, doses proven to work, or confirmation that mixing with specific commercial products is effective. So we don’t have a solid, research‑backed recipe saying “X milligrams of GHK in Y ml of hyaluronic acid gives benefit.” For someone curious about trying this at home, the practical takeaway is to be cautious. Using peptides topically with a compatible base product (like a water‑based serum) is a common practice among DIY skincare fans, and many sellers provide suggested concentrations. If you try it, start with low concentrations, patch‑test on a small skin area to check for irritation, and avoid sensitive areas like the eyes or open wounds. People worried about cosmetic aging or thinning hair might consider discussing options with a dermatologist, who can recommend evidence‑based treatments and safer ways to incorporate peptides if appropriate. There are important caveats. Over‑the‑counter peptides aren’t regulated like drugs, so quality, purity, and actual concentration can vary. Mixing products yourself can alter pH or stability and may reduce effectiveness or increase the risk of skin irritation or allergic reaction. People who are pregnant, breastfeeding, or have significant skin conditions should be especially cautious and consult a clinician. Also, some peptides are sold in powdered form and require sterile handling and correct solvents; improper preparation can be unsafe. Bottom line: GHK and AHK are promising in lab work but human evidence is limited; DIY mixing is common but carries quality and safety uncertainties, so start small, patch‑test, and consider professional advice.
Source: r/Peptides