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Someone on a forum asked for dosing advice for a proprietary “Mitoprime” peptide mix that combines NAD+, MOTS‑C, and 5‑Amino‑1MQ in a single small vial. They listed amounts in the vial (100 mg NAD+, 10 mg MOTS‑C, 10 mg 5‑Amino‑1MQ) and wanted tips on how much to take and how often. There’s no formal study or official dosing guidance mentioned in the post — it’s basically a user looking for practical instructions. Quickly, what these ingredients are: NAD+ is a small molecule involved in cell energy and metabolism; people sometimes take it because it’s linked to how cells produce energy. MOTS‑C is a short peptide (a tiny protein fragment) originally found in mitochondria that some lab studies say can influence metabolism and insulin sensitivity. 5‑Amino‑1MQ is a synthetic compound that has been researched in animals for effects on metabolism and fat tissue. None of these are household supplements like vitamin C; they’re experimental bioactive compounds that can affect cellular processes. The original post gives no clinical trial data or safety studies for this exact mix or for giving them together in humans. Most published MOTS‑C and 5‑Amino‑1MQ work has been in animals or in early lab research, not large human trials. NAD+ is used in various forms (oral, IV, supplements) with mixed evidence. Because the snippet is just a request for dosing, there’s no reliable evidence here about effective or safe doses, interactions between the three when combined, or long‑term outcomes. Any impression of benefit from a single anecdote online shouldn’t be taken as proof that it works or is safe. Why this matters to a regular person: people pursue peptides and metabolic mixes hoping to boost energy, lose weight, or slow aging. If you’re considering something like this, know that unregulated mixes can vary in purity and strength. Without tested dosing guidelines, you risk taking too little to do anything or too much and causing harm. Also, mixing compounds that haven’t been studied together can create unexpected effects. Anyone thinking about trying such a product should talk with a healthcare professional who understands these agents and, ideally, rely on products and protocols that have been clinically tested. Caveats and risks are important. These ingredients are not FDA‑approved as a combined treatment; many are experimental. Side effects can vary and haven’t been fully characterized in humans for all three, especially together. Peptides and experimental molecules can interfere with medications, metabolic conditions, or underlying health issues. There’s also the practical risk that online or compounding sources may mislabel or contaminate products. Pregnant or breastfeeding people, those with chronic illness, or anyone on prescription drugs should avoid experimenting without medical supervision. Bottom line: the post asks for dosing, but there’s no trustworthy dosing guidance available from that snippet — proceed cautiously and consult a qualified clinician.
Source: r/Peptides